作者
Berthold Langguth, Peter M Kreuzer, Tobias Kleinjung, Dirk De Ridder
发表日期
2013/9/1
来源
The Lancet Neurology
卷号
12
期号
9
页码范围
920-930
出版商
Elsevier
简介
Tinnitus is the perception of sound in the absence of a corresponding external acoustic stimulus. With prevalence ranging from 10% to 15%, tinnitus is a common disorder. Many people habituate to the phantom sound, but tinnitus severely impairs quality of life of about 1–2% of all people. Tinnitus has traditionally been regarded as an otological disorder, but advances in neuroimaging methods and development of animal models have increasingly shifted the perspective towards its neuronal correlates. Increased neuronal firing rate, enhanced neuronal synchrony, and changes in the tonotopic organisation are recorded in central auditory pathways in reaction to deprived auditory input and represent—together with changes in non-auditory brain areas—the neuronal correlate of tinnitus. Assessment of patients includes a detailed case history, measurement of hearing function, quantification of tinnitus severity, and …
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学术搜索中的文章
B Langguth, PM Kreuzer, T Kleinjung, D De Ridder - The Lancet Neurology, 2013