作者
Naoko Sasamoto, Long Ngo, Allison F Vitonis, Simon T Dillon, Stacey A Missmer, Towia A Libermann, Kathryn L Terry
发表日期
2022/9/1
期刊
Human Reproduction
卷号
37
期号
9
页码范围
2042-2053
出版商
Oxford University Press
简介
STUDY QUESTION
What are the systemic molecular profiles of endometriosis diagnosed in adolescents and young adults?
SUMMARY ANSWER
Significant enrichment and increased activation of proteins related to angiogenesis and cell migration pathways were observed in endometriosis cases compared to controls (P-value < 2.4 × 10−8).
WHAT IS KNOWN ALREADY
Little is known about the pathophysiology of adolescent endometriosis despite the fact that over 50% of adults with endometriosis report onset of severe pelvic pain during adolescence.
STUDY DESIGN, SIZE, DURATION
A cross-sectional analysis using data on 142 laparoscopically confirmed endometriosis cases and 74 controls from the observational longitudinal cohort of Women’s Health Study: From Adolescence to Adulthood (A2A …
学术搜索中的文章
N Sasamoto, L Ngo, AF Vitonis, ST Dillon, SA Missmer… - Human Reproduction, 2022
