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Image segmentation consists in partitioning an image into different regions. MRI image segmentation is especially interesting, since an accurate segmentation of the different brain tissues provides a way to identify many brain disorders such as dementia, schizophrenia or even the Alzheimer's disease. A large variety of image segmentation approaches have been implemented before. Nevertheless, most of them use a priori knowledge about the voxel classification, which prevents figuring out other tissue classes different from the classes the system was trained for. This paper presents two unsupervised approaches for brain image segmentation. The first one is based on the use of relevant information extracted from the whole volume histogram which is processed by using self-organizing maps (SOM). This approach is faster and computationally more efficient than previously reported methods. The second method …