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Two male siblings, aged 4.5 and 10 y respectively, of a nonconsanguinous family, presented with delayed milestones and epilepsy. The older sibling had frequent seizures since 7 y of age. Seizures were generalized-tonic-clonic and were poorly controlled on valproate, phenytoin and clobazam. His younger sibling had seizures (myoclonic and generalized tonicclonic) since 2.5 y of age with partial response to valproate, levetiracetam and clobazam. The inter-ictal EEG showed multifocal epileptiform discharges in the older sibling and infrequent bilateral frontal spike-wave-discharges in the younger sibling.