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This review provides an overview of therapeutic options, with a specific focus on the emerging role of medical options for UF management.

PubMed, Google Scholar, and Cochrane Systematic Reviews were searched for articles published between 1980 and 2013. Relevant articles were identified using the following terms: ‘uterine fibroids’, ‘leiomyoma’, ‘heavy menstrual bleeding’, and ‘menorrhagia’. The reference lists of articles identified were also searched for other relevant publications.

Because of the largely benign nature of UFs, the most conservative options that minimize morbidity/risk and optimize outcomes should be considered. Watchful waiting, or no immediate intervention combined with regular follow-up, is an appropriate option for the majority of UF patients who experience no symptoms. For women with symptomatic UFs, the optimal treatment should …