作者
Richard T Burnett, C Arden Pope III, Majid Ezzati, Casey Olives, Stephen S Lim, Sumi Mehta, Hwashin H Shin, Gitanjali Singh, Bryan Hubbell, Michael Brauer, H Ross Anderson, Kirk R Smith, John R Balmes, Nigel G Bruce, Haidong Kan, Francine Laden, Annette Prüss-Ustün, Michelle C Turner, Susan M Gapstur, W Ryan Diver, Aaron Cohen
发表日期
2014/4
期刊
Environmental health perspectives
卷号
122
期号
4
页码范围
397-403
出版商
National Institute of Environmental Health Sciences
简介
Background: Estimating the burden of disease attributable to long-term exposure to fine particulate matter (PM2.5) in ambient air requires knowledge of both the shape and magnitude of the relative risk (RR) function. However, adequate direct evidence to identify the shape of the mortality RR functions at the high ambient concentrations observed in many places in the world is lacking.
Objective: We developed RR functions over the entire global exposure range for causes of mortality in adults: ischemic heart disease (IHD), cerebrovascular disease (stroke), chronic obstructive pulmonary disease (COPD), and lung cancer (LC). We also developed RR functions for the incidence of acute lower respiratory infection (ALRI) that can be used to estimate mortality and lost-years of healthy life in children < 5 years of age.
Methods: We fit an integrated exposure–response (IER) model by integrating available RR information …
学术搜索中的文章
RT Burnett, CA Pope III, M Ezzati, C Olives, SS Lim… - Environmental health perspectives, 2014