作者
Nirav Thosani, Harvinder Singh, Asha Kapadia, Nobuo Ochi, Jeffrey H Lee, Jaffer Ajani, Stephen G Swisher, Wayne L Hofstetter, Sushovan Guha, Manoop S Bhutani
发表日期
2012/2/1
来源
Gastrointestinal endoscopy
卷号
75
期号
2
页码范围
242-253
出版商
Mosby
简介
BACKGROUND
The prognosis of esophageal cancer (EC) depends on the depth of tumor invasion and lymph node metastasis. EC limited to the mucosa (T1a) can be treated effectively with minimally invasive endoscopic therapy, whereas submucosal (T1b) EC carries relatively high risk of lymph node metastasis and requires surgical resection.
OBJECTIVE
To determine the diagnostic accuracy of EUS in differentiating T1a EC from T1b EC.
DESIGN
We performed a comprehensive search of MEDLINE, SCOPUS, Cochrane, and CINAHL Plus databases to identify studies in which results of EUS-based staging of EC were compared with the results of histopathology of EMR or surgically resected esophageal lesions. DerSimonian-Laird random-effects model was used to estimate the pooled sensitivity, specificity, and likelihood ratio, and a summary receiver operating characteristic (SROC) curve was created …
学术搜索中的文章
N Thosani, H Singh, A Kapadia, N Ochi, JH Lee, J Ajani… - Gastrointestinal endoscopy, 2012