作者
Sophie Patterson, Angela Cescon, Hasina Samji, Keith Chan, Wendy Zhang, Janet Raboud, Ann N Burchell, Curtis Cooper, Marina B Klein, Sean B Rourke, Mona R Loutfy, Nima Machouf, Julio SG Montaner, Chris Tsoukas, Robert S Hogg, CANOC collaboration
发表日期
2015/12
期刊
BMC infectious diseases
卷号
15
页码范围
1-10
出版商
BioMed Central
简介
Background
We sought to evaluate life expectancy and mortality of HIV-positive individuals initiating combination antiretroviral therapy (ART) across Canada, and to consider the potential error introduced by participant loss to follow-up (LTFU).
Methods
Our study used data from the Canadian Observational Cohort (CANOC) collaboration, including HIV-positive individuals aged ≥18 years who initiated ART on or after January 1, 2000. The CANOC collaboration collates data from eight sites in British Columbia, Ontario, and Quebec. We computed abridged life-tables and remaining life expectancies at age 20 and compared outcomes by calendar period and patient characteristics at treatment initiation. To correct for potential underreporting of mortality due to participant LTFU, we conservatively estimated 30 % mortality among participants lost to follow-up …
学术搜索中的文章
S Patterson, A Cescon, H Samji, K Chan, W Zhang… - BMC infectious diseases, 2015