作者
Simon M Cragg, Gregg T Beckham, Neil C Bruce, Timothy DH Bugg, Daniel L Distel, Paul Dupree, Amaia Green Etxabe, Barry S Goodell, Jody Jellison, John E McGeehan, Simon J McQueen-Mason, Kirk Schnorr, Paul H Walton, Joy EM Watts, Martin Zimmer
发表日期
2015/12/1
来源
Current opinion in chemical biology
卷号
29
页码范围
108-119
出版商
Elsevier Current Trends
简介
Highlights
- Biological lignocellulose deconstruction mechanisms are diverse.
- They are widely but sparsely dispersed across the Tree of Life.
- Some mechanisms operate at physico-chemical extremes of the biosphere.
- Diversity informs biotechnology for biofuels generation.
Organisms use diverse mechanisms involving multiple complementary enzymes, particularly glycoside hydrolases (GHs), to deconstruct lignocellulose. Lytic polysaccharide monooxygenases (LPMOs) produced by bacteria and fungi facilitate deconstruction as does the Fenton chemistry of brown-rot fungi. Lignin depolymerisation is achieved by white-rot fungi and certain bacteria, using peroxidases and laccases. Meta-omics is now revealing the complexity of prokaryotic degradative activity in lignocellulose-rich environments. Protists from termite guts and some oomycetes produce multiple lignocellulolytic enzymes. Lignocellulose-consuming …
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SM Cragg, GT Beckham, NC Bruce, TDH Bugg… - Current opinion in chemical biology, 2015