作者
Francesco Raimondi, Fiorella Migliaro, Iuri Corsini, Fabio Meneghin, Luca Pierri, Serena Salomè, Alessandro Perri, Salvatore Aversa, Stefano Nobile, Silvia Lama, Silvia Varano, Marilena Savoia, Sara Gatto, Valentina Leonardi, Letizia Capasso, Virgilio Paolo Carnielli, Fabio Mosca, Carlo Dani, Giovanni Vento, Pasquale Dolce, Gianluca Lista
发表日期
2021/12/1
期刊
Chest
卷号
160
期号
6
页码范围
2178-2186
出版商
Elsevier
简介
Background
Previous research shows that a lung ultrasound score (LUS) can anticipate CPAP failure in neonatal respiratory distress syndrome.
Research Question
Can LUS also predict the need for surfactant replacement?
Study Design and Methods
Multicenter, pragmatic study of preterm neonates who underwent lung ultrasound at birth and those given surfactant by masked physicians, who also were scanned within 24 h from administration. Clinical data and respiratory support variables were recorded. Accuracy of LUS, oxygen saturation to Fio2 ratio, Fio2, and Silverman score for surfactant administration were evaluated using receiver operating characteristic curves. The simultaneous prognostic values of LUS and oxygen saturation to Fio2 ratio for surfactant administration, adjusting for gestational age (GA), were analyzed through a logistic regression model.
Results
Two hundred forty infants were enrolled. One …
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F Raimondi, F Migliaro, I Corsini, F Meneghin, L Pierri… - Chest, 2021