作者
Rachael Jane Thorneloe, Rob Horne, Lucy Side, Michael Scott Wolf, Samuel George Smith, Vanessa Adamson, Sarah Ainsworth, Malin Akerlund, Ivanna Baker, Julian Barwell, Jayne Beesley, Lisa Brock, Chrissie Butcher, Janice Carpenter, Martyn Clark, Shirley Cocks, Veronica Conteh, Martina Coulding, Sue Darby, Angela Duckworth, Gareth Evans, Catherine Fensom, Julie Fletcher, Kate Foster, Sara Grieg, Elaine Gullaksen, Jana Gurasashvili, Lisa Hardstaff, Rachel Hart, Kathryn Hoare, Jonathan Hoffman, Christopher Holcombe, Lynne Horton, Antony Howell, Farah Islam, Emma Jenkinson, Karen Jewers, Manisha Joshi, Amy Kirkby, Peter Kneeshaw, Natalie Knife, Jalal Kokan, Jin Li, Nicola Lunt, Douglas Macmillan, Karen Makinson, Evangelos Mallidis, Sarah Manyangadze, Charity Masvaure, Raksha Mistry, Alice Ngumo, Jane Ooi, Ashraf Patel, Vanessa Pope, Laura Price, Fiona Rabson, Lisa Richardson, Stephanie Ridgway, Karen Riley, Lorraine Roberts, Janet Ryan-Smith, Vian Salih, Nicky Scott, Mike Shere, Andrew Sloan, Nita Solanky, Amanda Taylor, Dinesh Thekkinkattil, Heather Thomas, Mangesh Thorat, Barbara Townley, Jayant S Vaidya, Lynda Wagstaff, Shane Walsh, Lynsey Waring, Donna Watterson, Charlotte Westley, Lesley Wilkinson, Nicola Willis, Julia Wiseman
发表日期
2019/2/1
期刊
Clinical breast cancer
卷号
19
期号
1
页码范围
e116-e126
出版商
Elsevier
简介
Introduction
Uptake of preventive therapies for breast cancer is low. We examined whether women at increased risk of breast cancer can be categorized into groups with similar medication beliefs, and whether belief group membership was prospectively associated with uptake of preventive therapy.
Patients and Methods
Women (n = 732) attending an appointment to discuss breast cancer risk were approached; 408 (55.7%) completed the Beliefs About Medicines and the Perceived Sensitivity to Medicines questionnaires. Uptake of tamoxifen at 3 months was reported in 258 (63.2%). The optimal number of belief groups were identified using latent profile analysis.
Results
Uptake of tamoxifen was 14.7% (38/258). One in 5 women (19.4%; 78/402) reported a strong need for tamoxifen. The model fit statistics supported a 2-group model. Both groups held weak beliefs about their need for tamoxifen for current and future …
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RJ Thorneloe, R Horne, L Side, MS Wolf, SG Smith… - Clinical breast cancer, 2019