作者
Jamie W Bellinge, Frederik Dalgaard, Kevin Murray, Emma Connolly, Lauren C Blekkenhorst, Catherine P Bondonno, Joshua R Lewis, Marc Sim, Kevin D Croft, Gunnar Gislason, Christian Torp‐Pedersen, Anne Tjønneland, Kim Overvad, Jonathan M Hodgson, Carl Schultz, Nicola P Bondonno
发表日期
2021/8/17
期刊
Journal of the American Heart Association
卷号
10
期号
16
页码范围
e020551
简介
Background
Dietary vitamin K (K1 and K2) may reduce atherosclerotic cardiovascular disease (ASCVD) risk via several mechanisms. However, studies linking vitamin K intake with incident ASCVD are limited. We aimed to determine the relationship between dietary vitamin K intake and ASCVD hospitalizations.
Methods and Results
In this prospective cohort study, participants from the Danish Diet, Cancer, and Health Study, with no prior ASCVD, completed a food‐frequency questionnaire at baseline and were followed up for hospital admissions of ASCVD; ischemic heart disease, ischemic stroke, or peripheral artery disease. Intakes of vitamin K1 and vitamin K2 were estimated from the food‐frequency questionnaire, and their relationship with ASCVD hospitalizations was determined using Cox proportional hazards models. Among 53 372 Danish citizens with a median (interquartile range) age of 56 (52–60 …
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JW Bellinge, F Dalgaard, K Murray, E Connolly… - Journal of the American Heart Association, 2021