作者
Cassandra Smith, Marc Sim, Jack Dalla Via, Abadi K Gebre, Kun Zhu, Wai H Lim, Ryan Teh, Douglas P Kiel, John T Schousboe, Itamar Levinger, Stephan Von Haehling, Richard Woodman, Andrew JS Coats, Richard L Prince, Joshua R Lewis
发表日期
2024/2
期刊
Arteriosclerosis, thrombosis, and vascular biology
卷号
44
期号
2
页码范围
e54-e64
出版商
Lippincott Williams & Wilkins
简介
BACKGROUND
Abdominal aortic calcification (AAC), a marker of vascular disease, is associated with disease in other vascular beds including gastrointestinal arteries. We investigated whether AAC is related to rapid weight loss over 5 years and whether rapid weight loss is associated with 9.5-year all-cause mortality in community-dwelling older women.
METHODS
Lateral spine images from dual-energy x-ray absorptiometry (1998/1999) were used to assess AAC (24-point AAC scoring method) in 929 older women. Over 5 years, body weight was assessed at 12-month intervals. Rapid weight loss was defined as >5% decrease in body weight within any 12-month interval. Multivariable-adjusted logistic regression was used to assess AAC and rapid weight loss and Cox regression to assess the relationship between rapid weight loss and 9.5-year all-cause mortality.
RESULTS
Mean±SD age of women was 75.0 …
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C Smith, M Sim, J Dalla Via, AK Gebre, K Zhu, WH Lim… - Arteriosclerosis, thrombosis, and vascular biology, 2024