作者
Ayman A Zayed, Abdallah M Beano, Farah N Amer, Jumana M Maslamani, Mohammad A Zmaili, Talha H Al-Khudary, Munther S Momani, Al-Motassem F Yousef
发表日期
2016/11/1
期刊
Endocrine Practice
卷号
22
期号
11
页码范围
1310-1318
出版商
Elsevier
简介
Objective: To investigate whether serum carcinoembryonic antigen (CEA) levels are associated with type 2 diabetes mellitus (T2DM) and glycated hemoglobin (HbA1c).
Methods: A comparative, cross-sectional, observational study was conducted at Jordan University Hospital, Amman, Jordan, on 282 adult subjects from March 2012 to June 2015. Subjects were classified into 2 groups: T2DM subjects (n = 168) and a healthy comparison group (n = 114). Subjects with any condition known to be associated with elevated CEA levels were excluded. HbA1c and serum CEA levels were measured, and body mass index (BMI) was determined.
Results: Subjects with T2DM had significantly higher mean serum CEA than controls (2.4 ± 1.5 vs. 1.5 ± 1.2 ng/mL, P<.0001). Sex did not correlate with CEA levels, while age (Spearman's rho [ρ] = 0.18, P =.002) and HbA1c (ρ = 0.56, P<.0001) did; however, age no longer correlated …
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AA Zayed, AM Beano, FN Amer, JM Maslamani… - Endocrine Practice, 2016