作者
Charlien Gabriels, Pieter De Meester, Agnes Pasquet, Julie De Backer, Bernard P Paelinck, Marielle Morissens, Alexander Van De Bruaene, Marion Delcroix, Werner Budts
发表日期
2014/10/20
期刊
International journal of cardiology
卷号
176
期号
3
页码范围
833-840
出版商
Elsevier
简介
Background/objectives
Pulmonary arterial hypertension is an important complication in hemodynamically relevant atrial septal defects (ASD) and negatively affects outcome. This retrospective study aimed at (1) estimating the prevalence of pulmonary hypertension (PH) in patients with secundum ASD and (2) identifying predictors of PH development or persistence after ASD closure.
Methods
Consecutive patients with an isolated secundum ASD from the Belgian Registry on Adult Congenital Heart Disease were studied. Demographic, clinical, echocardiographic and invasive hemodynamic measurements were analyzed. PH was defined upon the echocardiographic PH probability (tricuspid regurgitation velocity ≥ 2.9 m/s).
Results
PH prevalence in the entire ASD population (295 patients, 68.8% females, mean age 46 ± 21 years) was 15.9% compared to 13.3% in patients after ASD closure. PH after ASD closure was …
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C Gabriels, P De Meester, A Pasquet, J De Backer… - International journal of cardiology, 2014