作者
Anna Melissa Guerrero, Anne Julienne Genuino, Melanie Santillan, Naiyana Praditsitthikorn, Varit Chantarastapornchit, Yot Teerawattananon, Marissa Alejandria, Jean Anne Toral
发表日期
2015/12
期刊
BMC public health
卷号
15
页码范围
1-17
出版商
BioMed Central
简介
Background
Cervical cancer is the second leading cause of cancer cases and deaths among Filipino women because of inadequate access to screening and treatment services.  This study aims to evaluate the health and economic benefits of HPV vaccination and its combination with different screening strategies to find the most optimal preventive strategy in the Philippines.
Methods
A cost-utility analysis was conducted using an existing semi-Markov model to evaluate different screening (i.e., Pap smear, visual inspection with acetic acid) and vaccination strategies against HPV infection implemented alone or as part of a combination strategy at different coverage scenarios. The model was run using country-specific epidemiologic, cost and clinical parameters from a health system perspective. Sensitivity analysis was performed for vaccine efficacy …
引用总数
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