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This is a novel study of phenolic content and synergistic effects between extracts and Eucalyptus globulus leaves essential oil and antibiotics against several isolates from respiratory tract infections (Pseudomonas aeruginosa). The extraction yield obtained with polar solvents was substantially higher, with the maximum value found for methanol 70%, followed by methanol 100% and water. Of the 16 isolates tested, only 4 (MJH 4, MJH 15, MJH 21 and MJH 40) revealed susceptibly to the extracts tested. The MJH 4 revealed the highest susceptibility of the 5 extracts tested (water, 70% methanol, 100% methanol, 100% acetone and 100% dichloromethane). The isolates tested showed the highest susceptibility to the extracts with higher phenolic compounds content, i.e. the methanolics. The highest inhibition halo value obtained was observed for the oil B against the isolate MJH 4 (19.3 mm), while the minimum value …