作者
Pranita D Tamma, Katherine E Goodman, Anthony D Harris, Tsigereda Tekle, Ava Roberts, Abimbola Taiwo, Patricia J Simner
发表日期
2017/2/1
期刊
Clinical Infectious Diseases
卷号
64
期号
3
页码范围
257-264
出版商
Oxford University Press
简介
Background
Carbapenem-resistant Enterobacteriaceae (CRE) are associated with considerable mortality. As mechanisms of carbapenem resistance are heterogeneous, it is unclear if mortality differs based on resistance mechanisms. We sought to determine whether CRE resistance mechanism determination is prognostically informative.
Methods
We conducted an observational study comparing 14-day mortality between patients with carbapenemase-producing (CP)-CRE compared with non-CP-CRE bacteremia. Clinical data were collected on all patients. A comprehensive DNA microarray-based assay was performed on all isolates to identify β-lactamase-encoding genes.
Results
There were 83 unique episodes of monomicrobial CRE bacteremia during the study period: 37 (45%) CP-CRE and …
学术搜索中的文章
PD Tamma, KE Goodman, AD Harris, T Tekle… - Clinical Infectious Diseases, 2017