作者
Samip N Patel, Marc A Cohen, Babak Givi, Benjamin J Dixon, Ralph W Gilbert, Patrick J Gullane, Dale H Brown, Jonathan C Irish, John R de Almeida, Kevin M Higgins, Danny Enepekides, Shao Hui Huang, John Waldron, Brian O'Sullivan, Wei Xu, Susie Su, David P Goldstein
发表日期
2016/4
期刊
Head & neck
卷号
38
期号
S1
页码范围
E658-E664
简介
Background
There are limited data on whether recurrent human papillomavirus (HPV)‐associated oropharyngeal squamous cell carcinoma (SCC) is associated with higher surgical salvage rates. The purpose of this study was to determine the success rate of salvage surgery for locally recurrent oropharyngeal cancer and factors influencing the outcome, including p16 status.
Methods
All patients who underwent salvage surgery for locally recurrent or persistent oropharyngeal cancer after (chemo)radiotherapy between 2000 and 2012 were included. The Kaplan–Meier analysis was used to determine overall survival (OS) and recurrence‐free survival (RFS). Univariable analysis was performed using Cox proportional hazards regression.
Results
Thirty‐four patients underwent salvage surgery. Five patients (14.7%) were tracheostomy dependent and 22 (64.7%) were gastrostomy tube dependent after salvage …
学术搜索中的文章
SN Patel, MA Cohen, B Givi, BJ Dixon, RW Gilbert… - Head & neck, 2016