作者
John R De Almeida, Murtadha Al Khabori, Gordon H Guyatt, Ian J Witterick, Vincent YW Lin, Julian M Nedzelski, Joseph M Chen
发表日期
2009/9/2
来源
Jama
卷号
302
期号
9
页码范围
985-993
出版商
American Medical Association
简介
Context
New evidence has emerged regarding the use of corticosteroids and antiviral agents in Bell palsy.
Objective
To estimate the association of corticosteroids and antiviral agents with the risk of unsatisfactory facial recovery in patients with Bell palsy.
Data Sources
The search included MEDLINE, EMBASE, CENTRAL, PsychInfo, CINAHL, Web of Science, PAPERSFIRST, PROCEEDINGSFIRST, and PROQUEST to identify studies up to March 1, 2009.
Study Selection and Data Extraction
Eligible studies were randomized controlled trials comparing treatment with either corticosteroids or antiviral agents with a control and measuring at least 1 of the following outcomes: unsatisfactory facial recovery (≥4 months), unsatisfactory short-term recovery (6 weeks to <4 months), synkinesis and autonomic dysfunction, or adverse effects. Two reviewers extracted data on study characteristics, methods, and outcomes …
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