作者
F Xavier Bosch, Thomas R Broker, David Forman, Anna-Barbara Moscicki, Maura L Gillison, John Doorbar, Peter L Stern, Margaret Stanley, Marc Arbyn, Mario Poljak, Jack Cuzick, Philip E Castle, John T Schiller, Lauri E Markowitz, William A Fisher, Karen Canfell, Lynette A Denny, Eduardo L Franco, Marc Steben, Mark A Kane, Mark Schiffman, Chris JLM Meijer, Rengaswamy Sankaranarayanan, Xavier Castellsagué, Jane J Kim, Maria Brotons, Laia Alemany, Ginesa Albero, Mireia Diaz, Silvia de Sanjosé
发表日期
2013/12/31
来源
Vaccine
卷号
31
页码范围
H1-H31
出版商
Elsevier
简介
Infection with human papillomavirus (HPV) is recognized as one of the major causes of infection-related cancer worldwide, as well as the causal factor in other diseases. Strong evidence for a causal etiology with HPV has been stated by the International Agency for Research on Cancer for cancers of the cervix uteri, penis, vulva, vagina, anus and oropharynx (including base of the tongue and tonsils). Of the estimated 12.7 million new cancers occurring in 2008 worldwide, 4.8% were attributable to HPV infection, with substantially higher incidence and mortality rates seen in developing versus developed countries. In recent years, we have gained tremendous knowledge about HPVs and their interactions with host cells, tissues and the immune system; have validated and implemented strategies for safe and efficacious prophylactic vaccination against HPV infections; have developed increasingly sensitive and specific …
学术搜索中的文章
FX Bosch, TR Broker, D Forman, AB Moscicki… - Vaccine, 2013