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A prominent deficit manifestation of intra-articular knee joint injury is quadriceps muscle weakness due to persistent muscular inhibition. Focal knee joint cooling (FKJC) has been shown as an effective intervention for improving quadriceps voluntary activation. However, there are gaps in the literature regarding the immediate effects of FKJC on the quadriceps' ability to initiate, rapidly develop, and maintain maximal force output. Therefore, the purpose of this study was to examine the immediate effects of FKJC on quadriceps neuromechanical function in individuals with a history of knee joint injury.