作者
Thomas G Cotter, Burhaneddin Sandıkçı, Sonali Paul, Anuhya Gampa, Jennifer Wang, Helen Te, Anjana Pillai, Kapuluru G Reddy, Diego di Sabato, Ester C Little, Vinay Sundaram, John Fung, Michael R Lucey, Michael Charlton
发表日期
2021/3/1
期刊
American Journal of Transplantation
卷号
21
期号
3
页码范围
1039-1055
出版商
Elsevier
简介
Medical-refractory severe alcoholic hepatitis (AH) has a high mortality. The national frequency, longer term outcomes and regional practices of AH liver transplantation (LT) in the United States are not well described, despite the increasing mortality from alcohol-associated liver disease. We analyzed the trends in frequency and outcomes of UNOS data on 39 455 adult patients who underwent LT from 2014 to 2019, including AH LT recipients. LTs for AH increased 5-fold, from 28 in 2014 to 138 in 2019, varying 8-fold between UNOS regions. Three transplant centers accounted for 50%-90% of AH LTs within each region. The number of transplant centers performing AH LTs increased from 14 in 2014 to 47 in 2019. AH patients were younger (mean = 39.4 years), had higher MELD scores (mean = 36.8), and were more often on dialysis (46.0%) and in ICU (38.4%), compared to other indications (all P < .05). One- and 5 …
引用总数
202020212022202320241718269