作者
Ivan Urits, Vwaire Orhurhu, Mark Jones, Dylan Hoyt, Allison Seats, Omar Viswanath
发表日期
2019/12
来源
Turkish journal of anaesthesiology and reanimation
卷号
47
期号
6
页码范围
439
出版商
Turkish Society of Anaesthesiology and Reanimation
简介
Postoperative cognitive dysfunction (POCD) is defined as a prolonged cognitive function impairment that occurs within weeks to months of a surgical procedure. It is especially prevalent in the elderly population, leading to increased morbidity and mortality. As anaesthetic and surgical care continues to improve and become increasingly safer, a significantly greater number of older patients have elective surgical procedures today, yet this comes with an increased POCD risk as they go through the perioperative phases. Although the pathophysiology behind the development of POCD is still under investigation, current causative mechanisms include the mode of anaesthesia administered, anaesthetic used, cerebral hypoperfusion, hyperventilation and neuroinflammation. These findings lend an insight into the importance of being cognisant of the higher likelihood of POCD in at-risk patients, including the elderly, and …
引用总数
2020202120222023202441628101
学术搜索中的文章
I Urits, V Orhurhu, M Jones, D Hoyt, A Seats… - Turkish journal of anaesthesiology and reanimation, 2019