作者
Philipp Rausch, Malte Rühlemann, Britt M Hermes, Shauni Doms, Tal Dagan, Katja Dierking, Hanna Domin, Sebastian Fraune, Jakob Von Frieling, Ute Hentschel, Femke-Anouska Heinsen, Marc Höppner, Martin T Jahn, Cornelia Jaspers, Kohar Annie B Kissoyan, Daniela Langfeldt, Ateequr Rehman, Thorsten BH Reusch, Thomas Roeder, Ruth A Schmitz, Hinrich Schulenburg, Ryszard Soluch, Felix Sommer, Eva Stukenbrock, Nancy Weiland-Bräuer, Philip Rosenstiel, Andre Franke, Thomas Bosch, John F Baines
发表日期
2019/12
期刊
Microbiome
卷号
7
页码范围
1-19
出版商
BioMed Central
简介
Background
The interplay between hosts and their associated microbiome is now recognized as a fundamental basis of the ecology, evolution, and development of both players. These interdependencies inspired a new view of multicellular organisms as “metaorganisms.” The goal of the Collaborative Research Center “Origin and Function of Metaorganisms” is to understand why and how microbial communities form long-term associations with hosts from diverse taxonomic groups, ranging from sponges to humans in addition to plants.
Methods
In order to optimize the choice of analysis procedures, which may differ according to the host organism and question at hand, we systematically compared the two main technical approaches for profiling microbial communities, 16S rRNA gene amplicon and metagenomic shotgun sequencing across our panel of …
引用总数
20192020202120222023202443070383723