作者
John R Hodges, Sasha Bozeat, Matthew A Lambon Ralph, Karalyn Patterson, Josef Spatt
发表日期
2000/9/1
期刊
Brain
卷号
123
期号
9
页码范围
1913-1925
出版商
Oxford University Press
简介
It has been reported that patients with semantic dementia function well in everyday life and sometimes show striking preservation of the ability to use objects, even those specific objects for which the patient has degraded conceptual information. To explore this phenomenon in nine cases of semantic dementia, we designed a set of semantic tests regarding 20 everyday objects and compared performance on these with the patients' ability to demonstrate the correct use of the same items. We also administered a test of mechanical problem solving utilizing novel tools, on which the patients had completely normal ability. All but the mildest affected patient showed significant deficits of naming and on the visually based semantic matching tasks. Object use was markedly impaired and, most importantly, correlated strongly with naming and semantic knowledge. In a small number of instances, there was appropriate …
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