作者
John G Armstrong, Louis B Harrison, Howard T Thaler, Hamutal Friedlander‐Klar, Daniel E Fass, Michael J Zelefsky, Jatin P Shah, Elliot W Strong, Ronald H Spiro
发表日期
1992/2/1
期刊
Cancer
卷号
69
期号
3
页码范围
615-619
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
To define the indications for elective neck treatment, the cases of 474 previously untreated patients were reviewed who had locally confined major salivary gland cancers treated between 1939 and 1982, Clinically positive nodes were present in 14% (67 of 474). Overall, clinically occult, pathologically positive nodes occurred in 12% (47 of 407). By univariate analysis, several factors appeared to predict the risk of occult metastases; however, multivariate analysis revealed that only size and grade were significant risk factors. Tumors 4 cm or more in size had a 20% (32 of 164) risk of occult metastases compared with a 4% (nine of 220) risk for smaller tumors [P < 0.00001). High‐grade tumors (regardless of histologic type) had a 49% (29 of 59) risk of occult metastases compared with a 7% (15 of 221) risk for intermediate‐grade or low‐grade tumors [P < 0.00001). In view of the low frequency of occult metastases in the …
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