作者
Francine van Wifferen, Lucie de Jonge, Joachim Worthington, Marjolein JE Greuter, Jie-Bin Lew, Claude Nadeau, Rosita van den Puttelaar, Eleonora Feletto, Jean HE Yong, Iris Lansdorp-Vogelaar, Karen Canfell, Veerle MH Coupé, COVID-19 and Cancer Global Modelling Consortium (CCGMC) working group 2
发表日期
2022/6
期刊
Journal of medical screening
卷号
29
期号
2
页码范围
72-83
出版商
SAGE Publications
简介
Objectives
Colorectal cancer (CRC) screening with a faecal immunochemical test (FIT) has been disrupted in many countries during the COVID-19 pandemic. Performing catch-up of missed screens while maintaining regular screening services requires additional colonoscopy capacity that may not be available. This study aimed to compare strategies that clear the screening backlog using limited colonoscopy resources.
Methods
A range of strategies were simulated using four country-specific CRC natural-history models: Adenoma and Serrated pathway to Colorectal CAncer (ASCCA) and MIcrosimulation SCreening ANalysis for CRC (MISCAN-Colon) (both in the Netherlands), Policy1-Bowel (Australia) and OncoSim (Canada). Strategies assumed a 3-month screening disruption with varying recovery period lengths (6, 12, and 24 months) and varying FIT thresholds for diagnostic colonoscopy. Increasing the FIT …
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