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Computed tomographic (CT) colonography is a new-generation technique for detecting colorectal neoplasms by using volumetric CT data combined with specialized imaging software. Patient examinations require full colonic preparation, insufflation, and data acquisition with the patient in the supine and prone positions. Current CT technology allows a single image of the colon to be acquired in as little as 20 seconds with a minimum of patient discomfort. Specialized computer software for interpretation usually combines transverse, multiplanar reformation, and three-dimensional endoluminal images for the optimal visualization of the colon and rectum. As of the time this article was written, CT colonography was competitive as a full structural colonic examination for the detection of polyps and cancer. To the authors’ knowledge, no study results have yet been reported in a screening population. The unique …