作者
Luca Zanoli, Mariarita Cannavo, Stefania Rastelli, Luigi Di Pino, Ines Monte, Marcella Di Gangi, Pierre Boutouyrie, Gaetano Inserra, Stephane Laurent, Pietro Castellino
发表日期
2012/9/1
期刊
Journal of hypertension
卷号
30
期号
9
页码范围
1775-1781
出版商
LWW
简介
Methods:
Thirty-two IBD patients without cardiovascular risk factors and 32 matched controls were enrolled (age 19–49 years). SphygmoCor device (AtCor Medical, Sydney, Australia) was used to measure carotid–femoral and carotid–radial (muscular artery) pulse wave velocity (PWV), augmentation index and central blood pressure.
Results:
Carotid–femoral PWV was higher in IBD patients than in controls (6.6±1.4 vs. 6.0±0.8 m/s, respectively, P< 0.05), as well as carotid–radial PWV (8.5±1.2 vs. 7.2±1.0 m/s, P< 0.001). Central pulse pressure was higher in IBD than in controls (32±6 vs. 28±7 mmHg, P< 0.05). Aging was an important determinant of carotid–femoral PWV in both groups and carotid–radial PWV only in IBD patients. In fully adjusted model performed in both groups of patients considered as a whole, age was positively associated with carotid–femoral PWV [R 2= 0.10;+ 0.05 m/s per 1 year of aging, 95 …
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L Zanoli, M Cannavo, S Rastelli, L Di Pino, I Monte… - Journal of hypertension, 2012