作者
Martin Van den Berg, Linda Birnbaum, AT Bosveld, Björn Brunström, Philip Cook, Mark Feeley, John P Giesy, Annika Hanberg, Ryuichi Hasegawa, Sean W Kennedy, Timothy Kubiak, John Christian Larsen, FX Van Leeuwen, AK Liem, Cynthia Nolt, Richard E Peterson, Lorenz Poellinger, Stephen Safe, Dieter Schrenk, Donald Tillitt, Mats Tysklind, Maged Younes, Fredrik Wærn, Tim Zacharewski
发表日期
1998/12
来源
Environmental health perspectives
卷号
106
期号
12
页码范围
775-792
简介
An expert meeting was organized by the World Health Organization (WHO) and held in Stockholm on 15-18 June 1997. The objective of this meeting was to derive consensus toxic equivalency factors (TEFs) for polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and dioxinlike polychlorinated biphenyls (PCBs) for both human, fish, and wildlife risk assessment. Based on existing literature data, TEFs were (re)evaluated and either revised (mammals) or established (fish and birds). A few mammalian WHO-TEFs were revised, including 1,2,3,7,8-pentachlorinated DD, octachlorinated DD, octachlorinated DF, and PCB 77. These mammalian TEFs are also considered applicable for humans and wild mammalian species. Furthermore, it was concluded that there was insufficient in vivo evidence to continue the use of TEFs for some di-ortho PCBs, as suggested earlier by Ahlborg et al. [Chemosphere …
引用总数
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