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Diabet. Med. 28, 1194–1200 (2011)

Aims  Omentin‐1 and chemerin have been identified as interesting novel adipokines that may modulate insulin action. Also, they have been suggested to be linked to obesity‐induced insulin resistance. The aim of this study was to analyse the relationship between these adipokines and interleukin‐6, insulin resistance and anthropometric and metabolic variables in patients with Type 2 diabetes mellitus and in patients with Type 2 diabetes who have ischaemic heart disease.

Methods  Seventy‐five individuals with Type 2 diabetes and 15 healthy control subjects were enrolled in this study. Insulin levels, interleukin‐6, omentin‐1 and chemerin were measured by ELISA.

Results  Serum omentin‐1 levels were found to be significantly decreased in patients with Type 2 diabetes (19.7 ± 1 ng/ml) and in patients with Type 2 diabetes with ischaemic heart disease …