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Micro(nano)-plastics (MP/NPs) ubiquity in the environment constitutes the global environmental and toxicological related issues of the 21st century. MP/NPs are now constantly observed in all components of the environment including many human consumer products; sea food, milk, beer, honey, bottle and tap water, salts, tea, drinks, and in human faeces and placenta. However, the potential health impacts in wildlife and humans are still poorly understood. This critical review provides comprehensive information on the ubiquity of MP/NPs in human consumer products, potential exposure route, uptake and translocation in the body and the associated pathophysiological effects. It also presents insight into the possible mechanisms that can lead to initiation and progression of cancer pathogenesis in the body. The possible mechanisms of MP/NPs induced cancer formation are centered on individual and or interactive …