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To compare the outcome of superovulation using clomiphene citrate (CC) versus hMG in conjunction with IUI.

Sequentially assigned, observational study. Couples initially were assigned to receive either CC or hMG for three cycles.

The Clinical Outpatient Department of the Dartmouth-Hitchcock Medical Center. Patient(s): Eighty-three infertile couples. Intervention(s): IUI with hMG use. Main Outcome Measure(s): Conception rate, term pregnancy rate (PR), and pregnancy complications, such as spontaneous miscarriage and multiple gestation. Result(s): Of 83 couples who underwent at least one treatment cycle, 29 (35%) conceived during the study period. The relative rate of conception for hMG versus CC was 2.08 (95% confidence interval [CI], 0.93 to 4.68). The relative term PR was 2.10 (95% CI, 0.77 to 5.73) for hMG versus CC. There was no difference in the miscarriage rate for hMG …