作者
David Araújo, Antônio C Santos, Tonicarlo R Velasco, Lauro Wichert‐Ana, Vera C Terra‐Bustamante, Veriano Alexandre Jr, Carlos G Carlotti Jr, Joao A Assirati Jr, Hélio Rubens Machado, Roger Walz, Joao P Leite, Américo C Sakamoto
发表日期
2006/8
期刊
Epilepsia
卷号
47
期号
8
页码范围
1354-1359
出版商
Blackwell Publishing Inc
简介
Purpose: We sought to analyze the contralateral volumes of the temporal pole, posterior segment of the temporal lobe, amygdala, hippocampus, and parahippocampal gyrus in patients with temporal lobe epilepsy (TLE) due to histologically proven mesial temporal lobe sclerosis (MTLS), seizure free for ≥4 years of postsurgical follow‐up.
Methods: Forty‐six (23 male) TLE patients, operated on between 1996 and 2001, with histopathologic diagnosis of MTLS, and a postsurgical follow‐up of ≥4 years, had their temporal lobe structures manually segmented, measured, and compared with those of 23 normal volunteers, paired as groups for sex, age, and handedness.
Results: The mean volumes of the contralateral temporal pole, hippocampus, and parahippocampal gyrus in TLE patients were significantly lower than those in controls.
Conclusions: MRI volumetric data show that the damage in TLE due to MTS may …
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D Araújo, AC Santos, TR Velasco, L Wichert‐Ana… - Epilepsia, 2006