作者
Gilaad G Kaplan, Cynthia H Seow, Subrata Ghosh, Natalie Molodecky, Ali Rezaie, Gordon W Moran, Marie-Claude Proulx, James Hubbard, Anthony MacLean, Donald Buie, Remo Panaccione
发表日期
2012/11/20
期刊
The American Journal of Gastroenterology
卷号
107
期号
12
页码范围
1879-1887
出版商
Nature Publishing Group
简介
OBJECTIVES:
Colectomy rates for ulcerative colitis (UC) have been inconsistently reported. We assessed temporal trends of colectomy rates for UC, stratified by emergent vs. elective colectomy indication.
METHODS:
From 1997 to 2009, we identified adults hospitalized for a flare of UC. Medical charts were reviewed. Temporal changes were evaluated using linear regression models to estimate the average annual percent change (AAPC) in surgical rates. Logistic regression analysis compared:(i) UC patients responding to medical management in hospital to those who underwent colectomy;(ii) UC patients who underwent an emergent vs. elective colectomy; and (iii) temporal trends of drug utilization.
RESULTS:
From 1997 to 2009, colectomy rates significantly dropped for elective colectomies with an AAPC of− 7.4%(95% confidence interval (CI):− 10.8%,− 3.9%). The rate of emergent colectomies remained stable with …
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