作者
Kien Vu Trung, Einas Abou-Ali, Fabrice Caillol, Woo H Paik, Bertrand Napoleon, Viliam Masaryk, Sophia E Van Der Wiel, Enrique Pérez-Cuadrado-Robles, Nicolas Musquer, Asif Halimi, Kevin Soares, Francois R Souche, Steffen Seyfried, Maria C Petrone, Stefano Crippa, Tobias Kleemann, David Albers, Tobias J Weismüller, Ana Dugic, Benjamin Meier, Edris Wedi, Moritz Schiemer, Sara Regner, Sebastien Gaujoux, Marcus Hollenbach, ESAP Study Group
发表日期
2023/8
期刊
Endoscopy
卷号
55
期号
08
页码范围
709-718
出版商
Georg Thieme Verlag KG
简介
Background Familial adenomatous polyposis (FAP) is a rare inherited syndrome that predisposes the patient to cancer. Treatment of FAP-related ampullary lesions is challenging and the role of endoscopic papillectomy has not been elucidated. We retrospectively analyzed the outcomes of endoscopic papillectomy in matched cohorts of FAP-related and sporadic ampullary lesions (SALs).
Methods This retrospective multicenter study included 1422 endoscopic papillectomy procedures. Propensity score matching including age, sex, comorbidity, histologic subtype, and size was performed. Main outcomes were complete resection (R0), technical success, complications, and recurrence.
Results Propensity score matching identified 202 patients (101 FAP, 101 SAL) with comparable baseline characteristics. FAP patients were mainly asymptomatic (79.2 % [95 %CI 71.2–87.3] vs. 46.5 % [95 %CI 36.6–56.4]); P …
引用总数