作者
James Dunbar, Konrad Krawczyk, Jinwoo Leem, Claire Marks, Jaroslaw Nowak, Cristian Regep, Guy Georges, Sebastian Kelm, Bojana Popovic, Charlotte M Deane
发表日期
2016/7/8
期刊
Nucleic acids research
卷号
44
期号
W1
页码范围
W474-W478
出版商
Oxford University Press
简介
SAbPred is a server that makes predictions of the properties of antibodies focusing on their structures. Antibody informatics tools can help improve our understanding of immune responses to disease and aid in the design and engineering of therapeutic molecules. SAbPred is a single platform containing multiple applications which can: number and align sequences; automatically generate antibody variable fragment homology models; annotate such models with estimated accuracy alongside sequence and structural properties including potential developability issues; predict paratope residues; and predict epitope patches on protein antigens. The server is available at http://opig.stats.ox.ac.uk/webapps/sabpred.
引用总数
201620172018201920202021202220232024289121432395323
学术搜索中的文章
J Dunbar, K Krawczyk, J Leem, C Marks, J Nowak… - Nucleic acids research, 2016