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Assessment of heart sounds which are generated by the beating heart and the resultant blood flow through it provides a valuable tool for cardiovascular disease (CVD) diagnostics. The cardiac auscultation using the classical stethoscope phonological cardiogram is known as the most famous exam method to detect heart anomalies. This exam requires a qualified cardiologist, who relies on the cardiac cycle vibration sound (heart muscle contractions and valves closure) to detect abnormalities in the heart during the pumping action. Phonocardiogram (PCG) signal represents the recording of sounds and murmurs resulting from the heart auscultation, typically with a stethoscope, as a part of medical diagnosis. For the sake of helping physicians in a clinical environment, a range of artificial intelligence methods was proposed to automatically analyze PCG signal to help in the preliminary diagnosis of different heart diseases. The aim of this research paper is providing an accurate CVD recognition model based on unsupervised and supervised machine learning methods relayed on convolutional neural network (CNN). The proposed approach is evaluated on heart sound signals from the well-known, publicly available PASCAL and PhysioNet datasets. Experimental results show that the heart cycle segmentation and segment selection processes have a direct impact on the validation accuracy, sensitivity (TPR), precision (PPV), and specificity (TNR). Based on PASCAL dataset, we obtained encouraging classification results with overall accuracy 0.87, overall precision 0.81, and overall sensitivity 0.83. Concerning Micro classification results, we obtained …