作者
Aristeidis H Katsanos, Theodora Psaltopoulou, Theodoros N Sergentanis, Alexandra Frogoudaki, Agathi‐Rosa Vrettou, Ignatios Ikonomidis, Ioannis Paraskevaidis, John Parissis, Chrysa Bogiatzi, Christina Zompola, John Ellul, Nikolaos Triantafyllou, Konstantinos Voumvourakis, Athanassios P Kyritsis, Sotirios Giannopoulos, Anne W Alexandrov, Andrei V Alexandrov, Georgios Tsivgoulis
发表日期
2016/4
来源
Annals of neurology
卷号
79
期号
4
页码范围
625-635
简介
Objective
Patent foramen ovale (PFO) can be detected in up to 43% of patients with cryptogenic cerebral ischemia undergoing investigation with transesophageal echocardiography (TEE). The diagnostic value of transthoracic echocardiography (TTE) in the detection of PFO in patients with cryptogenic ischemic stroke or transient ischemic attack has not been compared with that of transcranial Doppler (TCD) using a comprehensive meta‐analytical approach.
Methods
We performed a systematic literature review to identify all prospective observational studies of patients with cryptogenic cerebral ischemia that provided both sensitivity and specificity measures of TTE, TCD, or both compared to the gold standard of TEE.
Results
Our literature search identified 35 eligible studies including 3,067 patients. The pooled sensitivity and specificity for TCD was 96.1% (95% confidence interval [CI] = 93.0–97.8%) and 92.4 …
学术搜索中的文章
AH Katsanos, T Psaltopoulou, TN Sergentanis… - Annals of neurology, 2016