作者
Shahid Shafi, Ashley W Collinsworth, Laurel A Copeland, Gerald O Ogola, Taoran Qiu, Maria Kouznetsova, I-Chia Liao, Natalie Mears, An T Pham, George J Wan, Andrew L Masica
发表日期
2018/8/1
期刊
JAMA surgery
卷号
153
期号
8
页码范围
757-763
出版商
American Medical Association
简介
Importance
Opioids are commonly used for pain control during and after invasive procedures. However, opioid-related adverse drug events (ORADEs) are common and have been associated with worse patient outcomes.
Objectives
To examine the incidence of ORADEs in patients undergoing hospital-based surgical and endoscopic procedures and to evaluate the association of ORADEs with clinical and cost outcomes.
Design, Setting, and Participants
In this retrospective study of clinical and administrative data, ORADEs were identified usingInternational Classification of Diseases,Ninth Revisiondiagnosis codes for known adverse effects of opioids or by opioid antagonist use. Multivariable regression analysis was used to measure the association of ORADEs with outcomes after adjusting for potential confounding factors. The setting was 21 acute care hospitals in a large integrated health care delivery system …
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S Shafi, AW Collinsworth, LA Copeland, GO Ogola… - JAMA surgery, 2018
