作者
Dianne HK van Dam-Nolen, Martine TB Truijman, Anja G van Der Kolk, Madieke I Liem, Floris HBM Schreuder, Eric Boersma, Mat JAP Daemen, Werner H Mess, Robert J van Oostenbrugge, Antonius FW van Der Steen, Daniel Bos, Peter J Koudstaal, Paul J Nederkoorn, Jeroen Hendrikse, Aad van Der Lugt, M Eline Kooi, PARISK Study Group
发表日期
2022/10/1
期刊
Cardiovascular Imaging
卷号
15
期号
10
页码范围
1715-1726
出版商
American College of Cardiology Foundation
简介
Background
Patients with symptomatic carotid stenosis are at high risk for recurrent stroke. The decision for carotid endarterectomy currently mainly relies on degree of stenosis (cutoff value >50% or 70%). Nevertheless, also, patients with mild-to-moderate stenosis still have a considerable recurrent stroke risk. Increasing evidence suggests that carotid plaque composition rather than degree of stenosis determines plaque vulnerability; however, it remains unclear whether this also provides additional information to improve clinical decision making.
Objectives
The PARISK (Plaque At RISK) study aimed to improve the identification of patients at increased risk of recurrent ischemic stroke using multimodality carotid imaging.
Methods
The authors included 244 patients (71% men; mean age, 68 years) with a recent symptomatic mild-to-moderate carotid stenosis in a prospective multicenter cohort study. Magnetic …
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