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The Internet of Medical Things (IoMT) mobile devices such as ambulance, medical done, and emergency mobile medical equipment face severe signal distortions due to interference, end-to-end packet loss, handoff delays, and lower throughputs during mobility. Network mobility basic support protocol (NBSP) has been proposed using the IP-based Wi-Fi solution to solve these issues. However, the weak signal, extra signaling overhead, and higherdelays were identified during handover due to patients' excessive requisites, resulting in radio link failure. Therefore, this article proposes a novel resource-efficient flow-enabled distributed mobility anchoring (FDMA) framework enhancing the functionalities of the centralized network entities and mobility entities.The performance of the proposed FDMA framework is evaluated and compared with the standard NBSP and proxy NEMO (PNEMO) scheme in terms of the …