作者
Nicholas S Hendren, James A De Lemos, Colby Ayers, Sandeep R Das, Anjali Rao, Spencer Carter, Anna Rosenblatt, Jason Walchok, Wally Omar, Rohan Khera, Anita A Hegde, Mark H Drazner, Ian J Neeland, Justin L Grodin
发表日期
2021/1/12
期刊
Circulation
卷号
143
期号
2
页码范围
135-144
出版商
Lippincott Williams & Wilkins
简介
Background
Obesity may contribute to adverse outcomes in coronavirus disease 2019 (COVID-19). However, studies of large, broadly generalizable patient populations are lacking, and the effect of body mass index (BMI) on COVID-19 outcomes— particularly in younger adults—remains uncertain.
Methods
We analyzed data from patients hospitalized with COVID-19 at 88 US hospitals enrolled in the American Heart Association’s COVID-19 Cardiovascular Disease Registry with data collection through July 22, 2020. BMI was stratified by World Health Organization obesity class, with normal weight prespecified as the reference group.
Results
Obesity, and, in particular, class III obesity, was overrepresented in the registry in comparison with the US population, with the largest differences among adults ≤50 years. Among 7606 patients, in-hospital death or mechanical ventilation occurred in 2109 (27.7%), in …
引用总数