作者
Hasan Satış, Hasan Selçuk Özger, Pınar Aysert Yıldız, Kenan Hızel, Özlem Gulbahar, Gonca Erbaş, Gülbin Aygencel, Ozlem Guzel Tunccan, Mehmet Akif Öztürk, Murat Dizbay, Abdurrahman Tufan
发表日期
2021/1/1
期刊
Cytokine
卷号
137
页码范围
155302
出版商
Academic Press
简介
Background
The effectual immune response is crucial to defeat viral infections. However, exuberant immune response with features of macrophage activation syndrome (MAS) lead detrimental consequences in COVID-19 patients. Interleukin (IL)-18 is one of the leading cytokines in MAS which has not been studied in COVID-19.
Objective
To investigate the association of IL-18 with the other inflammatory markers and disease severity in COVID-19 for predicting disease prognosis.
Methods
Patients with COVID-19 who had confirmed diagnosis with SARS-CoV-2 nucleic acid RT-PCR were enrolled into the study. Data on demographic and clinical characteristics, and laboratory values of CRP, ferritin, d-dimer and procalcitonin were measured on admission. Patients were followed up prospectively with a standardized approach until hospital discharge or death. Individuals were classified as asymptomatic, mild and severe …
学术搜索中的文章
H Satış, HS Özger, PA Yıldız, K Hızel, Ö Gulbahar… - Cytokine, 2021