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Aims and objectives.  To understand the process of adaptation to dependency in older adults and their families.

Background.  Dependency and family care giving are attracting the attention of policymakers, service providers and researchers.

Design.  An interpretative synthesis of qualitative studies has been conducted.

Methods.  An extensive search without time and idiom limitations was conducted using the main databases (MEDLINE, CINAHL, EMBASE, PsycINFO, SSCI, LILACS, CUIDEN, Cochrane Library and JBI): personal communication from expert panel was used to detect filters strategies to find qualitative studies; these strategies were combined with search terms for dependence in older adults. The studies (2164 potentially relevant papers) were judged by two reviewers based on reading title, abstract, keywords and/or full text (English, Spanish, French and Portuguese) to determine their inclusion …