作者
Matthew J Budoff, John E Hokanson, Khurram Nasir, Leslee J Shaw, Gregory L Kinney, David Chow, Daniel DeMoss, Vivek Nuguri, Vahid Nabavi, Raghu Ratakonda, Daniel S Berman, Paolo Raggi
发表日期
2010/12
期刊
JACC: Cardiovascular Imaging
卷号
3
期号
12
页码范围
1229-1236
出版商
American College of Cardiology Foundation
简介
Objectives
This study examined a large cohort to assess whether progression of coronary artery calcium (CAC) was associated with all-cause mortality, and which among 3 different methods to assess CAC progression provided the best estimate of risk.
Background
Serial assessment of CAC scores has been proposed as a method to follow progression of coronary artery disease, and it has been suggested that excessive CAC progression may be a useful noninvasive predictor of the patient's risk of future events. However, the optimal method to measure calcium progression has not been well established.
Methods
The study sample consisted of 4,609 consecutive asymptomatic individuals referred by primary physicians for CAC measurement with electron beam tomography, who underwent repeat screening. Three general statistical approaches were taken: 1) the absolute difference between follow-up and baseline …
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MJ Budoff, JE Hokanson, K Nasir, LJ Shaw, GL Kinney… - JACC: Cardiovascular Imaging, 2010