作者
Lucy De La Cruz, Stephanie A Blankenship, Abhishek Chatterjee, Rula Geha, Nadia Nocera, Brian J Czerniecki, Julia Tchou, Carla S Fisher
发表日期
2016/10
来源
Annals of surgical oncology
卷号
23
页码范围
3247-3258
出版商
Springer International Publishing
简介
Background
Surgeons have increasingly performed breast-conserving surgery (BCS) utilizing oncoplastic techniques in place of standard lumpectomy for early-stage breast cancer. We assess oncologic outcomes after oncoplastic BCS for T1–T2 breast cancer.
Methods
A systematic literature review identified peer-reviewed articles in PubMed evaluating BCS with oncoplastic reconstruction. Selected studies reported on positive margin rate (PMR), re-excision rate (RR), conversion to mastectomy rate (CMR), overall survival (OS), disease-free survival (DFS), local recurrence (LR), distant recurrence (DR), complication rate, and/or cosmetic outcomes.
Results
The search yielded 474 articles; 55 met the inclusion criteria and collectively evaluated 6011 patients with a mean age 54.6 years over a mean follow-up 50.5 months …
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