作者
Julio Furlan, Michael Radan, Charles Tator
发表日期
2020/4/14
来源
Neurology
卷号
94
期号
15_supplement
页码范围
418
出版商
Lippincott Williams & Wilkins
简介
Objective
To review the definitions and scope of the clinical research on traumatic brain injury (mTBI)/concussion that was registered in the website www.clinicaltrials.gov from 2000 to June/2019.
Background
While many patients with concussion or mild mTBI recover completely, prolonged post-concussion symptoms remain a challenge for patients and an opportunity for research. This has led to numerous research initiatives over the last two decades, which were reviewed here.
Design/Methods
This scoping review included all clinical studies on diagnosis and management of patients with mTBI/concussion registered in the website www.clinicaltrials.gov from 2000 to June/2019. The terms “concussion, brain” were used for the primary search. Definitions of mTBI/concussion were obtained from the study protocols. When a definition was missing in the website, the study’s principal investigator was contacted for …