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BACKGROUND

While many patients with mild traumatic brain injury (mTBI) or concussion recover completely, prolonged postconcussion symptoms remain a challenge for patients and an opportunity for clinical research. This has led to numerous research initiatives over the last 2 decades.

OBJECTIVE

To review the characteristics of clinical studies on management of mTBI/concussion; and to examine their definitions of mTBI/concussion.

METHODS

This scoping review included all clinical studies on diagnosis and management of patients with mTBI/concussion registered at www. clinicaltrials. gov from 2000 to June/2019. The terms “mild TBI/concussion” were used for the primary search. Definitions of mTBI/concussion were obtained from the protocols. When a definition was missing in the website, the study's investigators were contacted for clarification.

RESULTS

There were 225 interventional and 95 observational …